Iodine December 6, 2021 See Hyperthyroidism & Goitre. Essential trace element required for normal thyroid gland function. Both deficiency and excess are capable of causing thyroid gland enlargement (goitre). Related Articles: Glossary: Hypothyroidism & GoiterGlossary: MineralsGlossary: Nitrates & NitritesGlossary: ThyroidGlossary: Trace Elements