An herbal remedy from which the underground tubers reputedly contain most of the active glycoside component harpagide. Marketed for use in humans for analgesic and anti-inflammatory effect it is used for joint and muscle pain, rheumatism, and arthritis. Horse studies are very limited and involved inclusion of the herbal extract in an herbal mixture. Whilst some anti-inflammatory effect on joint fluid markers was noted there was no improvement in lameness or flexion test scores. Testing of Devils Claw alone by a separate group of authors determined the product to be safe for oral administration and free of undesirable side effects. So, whilst the product appears to be safe at recommended dose rates or around 4g/Day, no therapeutic dose rate has been established for horses and nor has any beneficial effect been scientifically verified. Claims to the contrary should be viewed with caution.